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We have observed that the number of GPU cores makes the difference. As a simple rule we can say: the more GPU cores, the better. A simulation with a Nvidia NVIDIA Quadro K6000 (2880 cores) is about 3x faster than an Intel Core i7-3930K, for example.

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This is a typical effect when GPUs are not supported or when the GPU is slower than the CPU.

Is it possible to use multiple GPUs

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Sorry, currently not.

CUDA or OpenCL?

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