As explained under → “UI Panels and Windows” it is possible to configure RealFlow's layout to your needs: panels can be added and/or changed in size, and rearranged. All these changes are only temporary though, so they have to be saved:
...
The default place for the layout files is located in RealFlow's program directory and specified under “Preferences”→ “Preferences”:
Preferences > Layout > Layouts folder
...